In this film based on the William Gibson story, Johnny (Keanu Reeves) is a data courier who has a secret stash of information implanted into his mind. However, the data will kill Johnny if he cannot retrieve it within 48 hours.
Accompanied by physically enhanced bodyguard Jane (Dina Meyer), Johnny sets out to acquire the passwords he needs to save himself. Worse yet, he is hunted by gangster Shinji (Denis Akiyama) and businessman Takahashi (Takeshi), both of whom seek the data Johnny possesses.
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